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Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma
A comparative study to evaluate Efficacy and tolerability of new lotion in the treatment of Melasma.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Metformin 30% and 2% Nicotinamispde | Active Comparator | Metformin 30% plus Nicotinamide 2% in the reatment of Melasma |
|
| Kligman formula | Active Comparator | Kligman formula in the treatment of Melasma |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Metformin and Nicotinamide vs Kligman Formula | Drug | Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma |
|
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of 30% Metformin and 2% Nicotinamide lotion with kligman formula in the treatment of Melasma | Efficacy with measurement of MASI score 4 weeks apart | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ishtiaq Ahmed, MBBS | Pak Emirates Military Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| PakEmiratesMH | Rawalpindi | Punjab Province | Pakistan |
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| ID | Term |
|---|---|
| D008548 | Melanosis |
| ID | Term |
|---|---|
| D017495 | Hyperpigmentation |
| D010859 | Pigmentation Disorders |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D008687 | Metformin |
| ID | Term |
|---|---|
| D001645 | Biguanides |
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
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