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The aim was to compare placental oxygenation in low risk, uncompli-cated, term pregnancies measured by near-infrared spectroscopy (NIRS) in relation to the placental maturity grade determined by ultrasound assessment according to Grannum scale.
The study included 34 singleton subjects divided into two groups accord-ing to placental maturation: low grade (Grannum 0-1; n=10) and high grade (Gran-num 2-3; n=24). In each study subjects, measurement was performed at two sites: (a) test site above the central part of the placenta, and (b) control site out of placenta on lower abdomen, in medial line, 3 cm from the symphysis. Student's t-test was used to compare tissue oxygenation index (TOI) values among the study groups. The normality of distribution was demonstrated by the Kolmogorov-Smirnov test.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Grannum placental maturity grade 0 and 1 (low maturity level | Women with low placental maturity grade (group 1, Grannum 0-1) | ||
| Grannum placental maturity grade 2 and 3 (high maturity level) | Women with high placental maturity grade (group 2, Grannum 2-3) |
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| Measure | Description | Time Frame |
|---|---|---|
| Placental oxygenation levels | to compare placental oxygenation in low risk, uncomplicated, term pregnancies measured by near-infrared spectroscopy (NIRS) in relation to the placental maturity grade determined by ultrasound assessment according to Grannum scale. | During the procedure |
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Inclusion Criteria:
singleton pregnancies low-risk pregnancies uncomplicated pregnancies term pregnancies (37th to 41+6 weeks of gestation) anterior placental localization abdominal wall of less than 3cm thickness.
Exclusion Criteria:
complicated pregnancies pre-term pregnancies Abdominal wall tick > 3cm
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pregnant women with singleton low-risk, uncomplicated, term pregnancies anterior placental localization and abdominal wall of less than 3cm thickness. US and Doppler studies, as well as CTG and laboratory findings were normal in all study women.
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| Name | Affiliation | Role |
|---|---|---|
| Mislav Mikuš, M.D. | Clinical Hospital Centre Zagreb | Principal Investigator |
| Antonio Simone Laganà, M.D. Ph.D. | University of Palermo | Study Chair |
| Andrea Etrusco, M.D | University of Palermo | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hormona Polyclinic | Split | 21000 | Croatia |
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| ID | Term |
|---|---|
| D010922 | Placenta Diseases |
| ID | Term |
|---|---|
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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