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The aim of the study was to assess the values of cerebral oxygenation in full-term neonates in the first 10 minutes of life and to compare these values between neonates delivered by normal vaginal delivery and those delivered by elective cesarean section.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Neonates delivered by normal vaginal delivery |
| ||
| Neonates delivered by elective cesarean section. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Near-infrared spectroscopy | Device | Near-infrared spectroscopy (NIRS) offers the non-invasive continuous monitoring of cerebral oxygenation and perfusion. Cerebral regional oxygen (crSO2) measured via NIRS represents a mixed tissue saturation value, thus enabling information on the balance of cerebral oxygen delivery and oxygen consumption. |
| Measure | Description | Time Frame |
|---|---|---|
| Cerebral regional oxygen saturation monitoring (crSO2) | Measurements was done by using Near infrared spectroscopy (INVOSTM 5100C Cerebral/ Somatic Oximeter Monitor; Covidien) by placing a neonatal brain sensor on the left frontoparietal area of the newborn's head. | the first 10 minutes of life |
| Peripheral oxygen saturation monitoring (SpO2) | Oxygen saturation was measured using pulse oximeter (Masimo or Nellcor) by applying a preductal pulseoximetry sensor to the right wrist. | the first 10 minutes of life |
| Blood gas analysis | It was performed from umbilical cord blood. All newborns will be clinically observed and evaluated during this period by a neonatologist, and clinical status will be assessed by Apgar score. The Apgar score is based on a total score of 1 to 10. The higher the score, the better the baby is doing after birth. A score of 7, 8, or 9 is normal and is a sign that the newborn is in good health. | up to 10 minutes of life |
| Fractional tissue oxygen extraction (FTOE) | After measuring peripheral oxygen saturation (SpO2) and cerebral regional oxygen saturation (crSO2). For evaluation of the balance of oxygen delivery and oxygen consumption, calculation of the fractional tissue oxygen extraction can be done using the following equation: FTOE=(SpO2-crSO2)/SpO2 | up to 10 minutes of life |
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Inclusion Criteria:
Exclusion Criteria:
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Full term neonates born either via normal vaginal delivery or elective cesarean section.
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| Name | Affiliation | Role |
|---|---|---|
| Alaa IA Ibrahim, MBBCh | Faculty of Medicine, Alexandria University, Egypt | Principal Investigator |
| Hesham A Ghazal, PhD | Faculty of Medicine, Alexandria University, Egypt | Study Director |
| Marwa M Farag, PhD | Faculty of Medicine, Alexandria University, Egypt | Study Chair |
| Bahaa S Hammad | Faculty of Medicine, Alexandria University, Egypt | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Neonatal Intensive Care Unit (NICU) of Alexandria University Maternity Hospital. | Alexandria | 21131 | Egypt |
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| ID | Term |
|---|---|
| D019265 | Spectroscopy, Near-Infrared |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D013057 | Spectrum Analysis |
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| D002623 |
| Chemistry Techniques, Analytical |
| D008919 | Investigative Techniques |