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Pilot testing and development of an immersive virtual reality system for spatial navigation training in mild cognitive impairment syndrome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CAVE | Experimental | 10 immersive virtual reality sessions to train spatial memory |
|
| TAU | Active Comparator | 10 paper and pencil sessions to train spatial memory |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CAVE | Other | The training is designed to train spatial navigation and memory and in particular egocentric and allocentric processes |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Corsi supra-span test | Scores range from 0 to 29.16, higher scores indicate better visuospatial learning | After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up |
| Change in Manikin Test | Scores range from 0 to 1, higher scores indicate better visuospatial mental rotation | After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| Trail-making test part A and B | After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up | |
| Raccontino (6 Dicembre) (immediate-delayed-forgetting) | After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cosimo Tuena | Milan | Lombardy | 20145 | Italy |
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| D065854 | Spatial Navigation |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D013037 | Spatial Behavior |
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| ID | Term |
|---|---|
| D059552 | Caves |
| ID | Term |
|---|---|
| D055593 | Geological Phenomena |
| D055585 | Physical Phenomena |
| D004777 | Environment |
| D055669 | Ecological and Environmental Phenomena |
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Proof-of-concept trial
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| TAU | Other | This is the usual care used to train visuospatial processes |
|
| Mini-mental state examination | After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up |
| Digit span forward | After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up |
| Corsi Block Tapping | After 10 training sessions (3/4 weeks approx.) and after 3-month follow-up |
| D001519 |
| Behavior |
| D001686 | Biological Phenomena |
| D004778 | Environment and Public Health |