This is a prospective observational study aiming to evaluate the diagnostic accuracy of the high-sensitivity Troponin assay performed with the Atellica VTLi POCT system (by comparison with the results obtained with the Atellica diagnostic system currently in use) and to evaluate the impact of the POCT system on the reduction of decision-making time (particularly of "rule-out"), by evaluating the number of cases in which the conclusion of the decision pathway at 3 h (algorithm currently in use) could have been concluded at 1 h.

Patients accessing the emergency room for chest pain suspected of acute myocardial ischemia, who are asked for Troponin determination for the decision pathway, will be asked to participate at the study. A blood draw will be performed (for determination of Troponin value, with classical method in use and with POCT method) at time:

• Zero (acess at the emergency room)
• 1 h
• 3 h

Inclusion Criteria:

• Emergency department access for acute non-traumatic chest pain suspected of myocardial ischemia
• Sign of Informed Consent

Exclusion Criteria:

• Diagnostic electrocardiographic picture for Acute Coronary Syndrome-STEMI (ACS-STEMI)
• Absence of symptomatology in the 12 hours prior to admission to the emergency room
• Post-traumatic chest pain

Patients accessing at emergency room for acute chest pain suspected of acute myocardial ischemia, who are asked for Troponin determination in the pathway decision-making.