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| Name | Class |
|---|---|
| University of Central Florida | OTHER |
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The purpose of this investigation is to examine the effects of consuming a new dietary microalgae based supplement vs. placebo on neuromuscular function, energy utilization, soreness, perceptual wellness, swelling, and markers of muscle damage and inflammation in healthy young men before and after an acute exercise-induced muscle damage protocol (downhill running), and influence on endurance capacity after prolonged consumption.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo group | Placebo Comparator | 2 capsules of Maltodextrin per day |
|
| MicAlgae100 | Experimental | 2 capsules per day containing 100mg of microalgae based ingredient |
|
| MicAlgae250 | Experimental | 2 capsules per day containing 250mg of microalgae based ingredient |
|
| MicAlgae500 | Experimental | 2 capsules per day containing 500mg of microalgae based ingredient |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MicAlgae | Dietary Supplement | 2 months of supplementation with an innovative microalgae based ingredient |
|
| Measure | Description | Time Frame |
|---|---|---|
| Neuromuscular function | isokinetic peak torque in Newton per meter (N/m) | From 0 to week 4 |
| Measure | Description | Time Frame |
|---|---|---|
| Energy utilization (Oxygen consumption - VO2) | Running economy during a 5-minute run at 80% of the speed at VO2max with gaz exchange analyzis | From 0 to week 4 |
| Energy utilization (Oxygen consumption - VO2) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| David Fukuda, PhD | University of Central Florida | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Central Florida | Orlando | Florida | 32816 | United States |
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| ID | Term |
|---|---|
| D007249 | Inflammation |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Placebo | Dietary Supplement | 2 months of supplementation with a placebo (Maltodextrin) |
|
Running economy during a 5-minute run at 80% of the speed at VO2max with gaz exchange analyzis
| From 0 to week 8 |
| Isokinetic neuromuscular function | peak torque in Newton per meter (N/m) | From 0 to week 8 |
| Isometric neuromuscular function | peak torque in Newton per meter (N/m) | From 0 to week 8 |
| Endurance capacity | Maximal oxygen consumption (VO2max) determined during graded exercise test | From 0 to week 4 |
| Endurance capacity | Maximal oxygen consumption (VO2max) determined during graded exercise test | From 0 to week 8 |
| Soreness and perceptual wellness | Evaluated using using a 100-point numerical pain rating scale anchored with 0= no pain to 100= the most intense pain sensation imaginable after exercise-induced muscle damage protocol | From 0 to week 4 |
| Soreness and perceptual wellness | Evaluated using using a 100-point numerical pain rating scale anchored with 0= no pain to 100= the most intense pain sensation imaginable after exercise-induced muscle damage protocol | From 0 to week 8 |
| Swelling - Muscle thickness (mm or cm) | Evaluated using musculoskeletal ultrasound | From 0 to week 4 |
| Swelling - overall thigh circumference (mm or cm) | Evaluated using musculoskeletal ultrasound | From 0 to week 4 |
| Creatine kinase (UI/I) | Blood marker analyzis | After 4 weeks of supplementation |
| lactate dehydrogenase (U/L) | Blood marker analyzis | After 4 weeks of supplementation |
| Myoglobin (ug/l) | Blood marker analyzis | After 4 weeks of supplementation |
| Interleukin-6 (pg/ml) | Blood marker analyzis - inflammation | After 4 weeks of supplementation |
| Tumor necrosis factor-α (ug/ml) | Blood marker analyzis - inflammation | After 4 weeks of supplementation |
| C-reactive protein (mg/l) | Blood marker analyzis - inflammation | After 4 weeks of supplementation |
| Isometric Neuromuscular function | Peak torque in Newton per meter (N/m) | From 0 to week 4 |