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| Name | Class |
|---|---|
| Huizhou Municipal Central Hospital | OTHER |
| Second Affiliated Hospital of Nanchang University | OTHER |
| Meng Chao Hepatobiliary Hospital of Fujian Medical University | OTHER |
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Tumor micronecrosis is a pathological feature that reflects malignant biological behavior in hepatocellular carcinoma (HCC). This study aimed to evaluate the prognostic significance of tumor micronecrosis based on the current BCLC and TNM staging systems, and futher improve the performance of the staging models by establishing modified new staging models including tumor micronecrosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| micronecrosis(+) group | Hepatocellular patients with tumor micronecrosis. |
| |
| micronecrosis(-) group | Hepatocellular patients without tumor micronecrosis. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| tumor micronecrosis | Behavioral | whether HCC patients have tumor micronecrosis or not |
|
| Measure | Description | Time Frame |
|---|---|---|
| Overall survival | the number of months from the date of surgery to the date of the last follow-up visit or time of death. | from date after liver resection until death or last follow-up, whichever came first, assessed up to 72 months |
| Measure | Description | Time Frame |
|---|---|---|
| Disease-free survival | the number of months from the date of surgery to the date of first confirmable recurrence or death | from date after liver resection until recurrence or last follow-up, whichever came first, assessed up to 72 months |
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Inclusion Criteria:
Exclusion Criteria:
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This retrospective study enrolled patients who underwent liver resection from four institutions in China: the First Affiliated Hospital, Zhejiang University School of Medicine (FAHZU) (n = 896), Mengchao Hepatobiliary Hospital of Fujian Medical University (n = 94), the Second Affiliated Hospital of Nanchang University (n = 84), and Huzhou Central Hospital (n = 36).
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| the First Affiliated Hospital, School of Medicine, Zhejiang University | Hangzhou | Zhejiang | 310003 | China | ||
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| ID | Term |
|---|---|
| D006528 | Carcinoma, Hepatocellular |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| the First Affiliated Hospital, School of Medicine, Zhejiang University |
| Hangzhou |
| Zhejiang |
| 310009 |
| China |
| D009369 | Neoplasms |
| D008113 | Liver Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D004066 | Digestive System Diseases |
| D008107 | Liver Diseases |