Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 2022-A02437-36 | Other Identifier | ANSM | |
| RECHMPL22_0504 | Other Identifier | CHU de Montpellier |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Asthma is the most common chronic lung disease in children. It affects more than 1 in 10 children in France. The methacholine bronchial challenge test (MBT) is indicated to assess the probability of asthma suggested by clinical symptoms by measuring the forced expiratory volume in one second (FEV1), after inhalation of a cumulative dose of methacholine. In children, the measurement of FEV1 requires a high level of cooperation from the child, which can be the source of false negatives or no result if this is not obtained. The objective of this study is to evaluate if the measurement of the respiratory function by the forced oscillations technique, allows to predict the variation of the FEV1 obtained
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Single Arm | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Airway Oscillation System | Procedure | After each methacholine dose administred, respiratory function will be measured by forced oscillation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in lung impedance measurement | Percentage change in lung impedance measurement obtained by the forced oscillation technique in relation to the dose of methacholine required to obtain bronchial hyperresponsiveness | During the procedure |
| Measure | Description | Time Frame |
|---|---|---|
| Average number of trials required for measurement of FEV1 with the spirometry technique | Average number of trials required for technically satisfactory iterative measurement of FEV1 | During the procedure |
| Average number of trials required for impedance measurement by forced oscillation |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Stefan MATECKI, MD | Contact | +33 4 67 33 59 12 | Stephan.matecki@umontpellier.fr | |
| Anne REQUIRAND | Contact | a-requirand@chu-montpellier.fr |
| Name | Affiliation | Role |
|---|---|---|
| Stefan MATECKI, MD | Montpellier Univerty Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Montpellier | Recruiting | Montpellier | France |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D001249 | Asthma |
| D004194 | Disease |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
Not provided
Not provided
Each subject is his or her own control
Not provided
Not provided
Not provided
Not provided
Average number of trials required for technically satisfactory iterative measurement of impedance |
| During the procedure |
| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |