This diagnostic study will use 410 retrospectively captured fundal videos to develop ML systems that detect SVPs and quantify ICP. The ground truth will be generated from the annotations of two independent, masked clinicians, with arbitration by an ophthalmology consultant in cases of disagreement.

Inclusion Criteria:

• Patients aged ≥18 years with presumed normal ICP undergoing routine dilated OCT scans.
• Patients undergoing a LP or continuous ICP monitoring with implanted transcranial pressure transducer devices at in- or out-patient neurology, neurosurgery or neuro-ophthalmology services.

Exclusion Criteria:

• Glaucoma diagnosis or glaucoma suspects in either eye.
• Bilateral restricted fundal view, e.g. advanced bilateral cataracts.
• Bilateral retinal vein or artery occlusion.

Patients aged ≥18 years with presumed normal ICP or suspected raised ICP

The data would be shared, where possible, through a restricted-access data sharing agreement, where in line with KCL data governance requirements.

Within 12 months of study completion

Data sharing agreement and data governance