Follow-up of the Nasal Microbiome and Viral Infections in Newborns Hospitalised in Neonatology.

Follow-up of the Nasal Microbiome and Viral Infections in Newborns Hospitalised in Neonatology in the University Hospital of Caen, France : Metatranscriptomics Approach by Next Generation Sequencing From Nasal Swabs.

The goal of this interventional study is to learn about nasal microbiome and viral infections in newborns hospitalised in neonatology.

The main questions it aims to answer are :

• how often are newborns infected by viruses in neonatology ?
• how does the microbiome develop during first weeks of life ?
• how does microbiome and viruses interacts together ?
• is there a link between viral infection, microbiome, and medical complications during hospitalisation in neonatology ? Participants will have a nasal swab taken each week during their hospitalisation in neonatology, and researchers will take medical data from the medical chart.

Inclusion Criteria:

• newborn hospitalised in neonatal intensive care unit during the inclusion period
• parents have been informed about the study (speaking french) and have signed the informed consent.
• affiliated to the social security system.

Exclusion Criteria:

• parental refusal
• minor parents or under judicial protection
• newborn who already have been discharded home before inclusion
• hospitalisation after the first 48 hours of life
• only palliative care