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Comparison of mechanical powers produced at volume controlled and pressure controlled mechanical ventilation
The mechanical power created by mechanical ventilation, as a new concept, can enable to evaluate the effect of different components in the lung.Our aim in this study is to calculate mechanical power in different ventilation modes ( pressure controlled and volume controlled ventilation) and to compare them. To calculate the mechanical powers we will use Van der Meijden's mechanical power formula for pressure controlled ventilation and for volume controlled ventilation we will use Gattinoni's mechanical power formula. In the literature we haven't seen any publication comparing the mechanical power of two commonly used ventilation modes (volume controlled and pressure controlled ventilation)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | Other | group 1 starts with volume controlled ventilation |
|
| Group 2 | Other | group 2 starts with pressure controlled ventilation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Starting with volume controlled ventilation and changing the ventilation mode every 20 minutes | Other | group 1 starts with volume controlled ventilation and we take three consecutive measurements in twenty minutes , after twenty minutes we change the ventilation mode to pressure controlled ventilation after letting washout we take three consecutive measurements at pressure controlled ventilation and we will repeat this protocol during surgery |
| Measure | Description | Time Frame |
|---|---|---|
| calculation of mechanical power changes in two different ventilation modes | mechanical power will be calculated using the Van der Meijden's formula for pressure support ventilation and Gattinoni's formula for volume controlled ventilation and two mechanical powers will be compared | change from at the beginning of surgery till the end of surgery |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative pulmonary complications | postoperative pulmonary complication including pneumonia, acute lung injury, respiratory failure requiring reintubation | post-operative 7 days |
| hospitalisation time |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Istanbul University | Istanbul University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul University, Department of Anesthesiology | Istanbul | 34093 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28701178 | Background | Gattinoni L, Marini JJ, Collino F, Maiolo G, Rapetti F, Tonetti T, Vasques F, Quintel M. The future of mechanical ventilation: lessons from the present and the past. Crit Care. 2017 Jul 12;21(1):183. doi: 10.1186/s13054-017-1750-x. | |
| 31359082 | Background | van der Meijden S, Molenaar M, Somhorst P, Schoe A. Calculating mechanical power for pressure-controlled ventilation. Intensive Care Med. 2019 Oct;45(10):1495-1497. doi: 10.1007/s00134-019-05698-8. Epub 2019 Jul 29. No abstract available. |
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|
| Starting with pressure controlled ventilation and changing the ventilation mode every 20 minutes | Other | group 2 starts with pressure controlled ventilation and we take three consecutive measurements in twenty minutes , after twenty minutes we change the ventilation mode to volume controlled ventilation after letting washout we take three consecutive measurements at volume controlled ventilation and we will repeat this protocol during surgery |
|
up to 20 days
| up to 20 days |