The aim of the study is to evaluate the safety and efficacy of diosmin as adjuvant therapy in treatment of non-bleeding peptic ulcer patients.

Inclusion Criteria:

-. Age 25-65 years old.

• Patients of both gender (male and female).
• Non-bleeding Peptic ulcer Patients (duodenal &gastric) diagnosed by endoscopy.

Exclusion Criteria:

• The presence of other factors that can lead to gastric bleeding other than peptic ulcer.

  • Patients with cancerous disease
  • Breast-feeding.
  • Surgically altered stomach ( bariatric surgery),
  • Patient with liver disease.

• Bleeding & perforated peptic ulcer.