Effect of Intake of Allium Cepa L. Peel Heated Water Extract on Immunity Enhancement

A 8 Weeks, Randomized, Double-blind, Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Allium Cepa L. Peel Heated Water Extract on Immunity Enhancement

This study was conducted to investigate the effects of daily supplementation of Allium Cepa L. Peel Heated Water Extract on Immunity Enhancement

This study was a 8 weeks, randomized, double-blind, placebo-controlled human trial. 40 subjects were randomly divided into Allium Cepa L. Peel Heated Water Extract or a placebo group. Immunity Enhancement profiles before and after the intervention.

Inclusion Criteria:

• Age 19-75 years
• Symptoms of upper respiratory infection at least once within past 12 months

Exclusion Criteria:

• Cardio-cerebrovascular, endocrine, immune, respiratory, musculoskeletal, inflammatory, hematologic, tumorigenic, gastrointestinal diseases, etc.
• Vaccination within past 2 months
• BMI < 18.5 kg/m2 or 35 kg/m2 ≤ BMI
• Immunity enhancement agents within past one months
• Allergic or hypersensitive to any of the ingredients in the test products
• Antipsychotic drugs therapy within past 3 months
• History of alcoholism or drug abuse
• Participation in any other clinical trials within past 3 months
• Pregnant or lactating women
• Judged ineligible to participate in the trial by the principal investigator