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| Name | Class |
|---|---|
| Bio Port Korea Inc. | OTHER |
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This randomized, placebo-controlled, double-blind study evaluates the efficacy and tolerability of Ulmus macrocarpa water extract for immunity improvement in relatively healthy adults. 58 subjects received 500 mg of Ulmus macrocarpa water extract per day or a placebo for 4 weeks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ulmus | Active Comparator | Ulmus macrocarpa water extract 250mg orally 2 times a day for 4 weeks |
|
| Placebo | Placebo Comparator | placebo 250mg orally 2 times a day for 4 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ulmus macrocarpa water extract | Dietary Supplement |
|
| Measure | Description | Time Frame |
|---|---|---|
| serum natural killer cell activity | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| peripheral white blood cell | 1 month | |
| serum tumor necrosis factor-alpha level | 1 month | |
| serum interferon-gamma |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29681977 | Derived | Cho AR, Lee SY, Cho YH, Kim CM, Kim SG. Effects of 4-Week Intervention with Ulmus macrocarpa Hance Extract on Immune Function Biomarkers in Healthy Adults: A Randomized Controlled Trial. Evid Based Complement Alternat Med. 2018 Feb 25;2018:5690816. doi: 10.1155/2018/5690816. eCollection 2018. |
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| 1 month |
| serum interleukins(1betta, 2,4,8,10, and 12) | 1 month |