Comparing Efficacy of Azithromycin and Probiotics for Treatment of Acne Vulgaris

Comparing Efficacy of Azithromycin and Probiotics for Treatment of Acne Vulgaris

the goal of this clinical trial is to measure the efficacy of probiotics for treatment of acne vulgaris, to compare it with azithromycin and to measure the synergistic effect of azithromycin and probiotics for treatment of acne vulgaris

this study aims to answer this research question: in patients of acne vulgaris, is use of probiotics as efficacious as azithromycin in treating acne lesions & improving quality of life? total 75 patients were divided into 3 groups. group A received azithromycin, group B received probiotics and group C received both drugs. a topical cream was also advised to all groups. outcome was measured as reduction in total lesion count and improvement in patients' quality of life via reduction in Dermatology Life Quality Index score.

Inclusion Criteria:

• Diagnosed Patients of Mild and Moderate acne
• Aged between 15 and 35 years

Exclusion Criteria:

• Severe acne or any systemic inflammatory disease
• Other oral treatment for acne
• Allergic to any drug being used in the study
• Pregnancy
• PCOs
• Any drug which can interact with azithromycin