Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Thyroidectomy

Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Thyroidectomy

Acetaminophen and ibuprofen has been safely used for a long time and reduces postoperative pain and opioid dosages. Investigators are planning to compare the efficacy of 1) acetaminophen only and 2) acetaminophen and ibuprofen combination at postoperative pain after thyroidectomy.

Acetaminophen and ibuprofen has been safely used for a long time and reduces postoperative pain and opioid dosages. Investigators are planning to compare the efficacy of 1) acetaminophen 1g only and 2) the combination of acetaminophen 1g and ibuprofen 300mg at postoperative pain after thyroidectomy. Some recovery valuables such as the postoperative pain and opioid requirements will be assessed

Inclusion Criteria:

• the patients undergoing scheduled thyroidectomy
• American Society of Anesthesiologists status 1 or 2

Exclusion Criteria:

• refusal to be enrolled in the study
• emergency surgery
• hepatic or renal disease
• on chronic pain medications
• psychiatric disorders
• pregnancy, lactation
• allergy or contraindication to the study drug