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| Name | Class |
|---|---|
| Oslo University Hospital | OTHER |
| University of Oslo | OTHER |
| The Hospital of Vestfold | OTHER |
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Anxiety and depression are associated with work disability, lower participation rate in cardiac rehabilitation and unfavourable life style changes following a coronary heart disease (CHD) event. The prevalence of clinically significant symptoms of depression and anxiety in CHD patients has been estimated to 30-50%. Furthermore, depression and anxiety are associated with a significant increased risk of subsequent major adverse cardiovascular events and mortality in CHD patients. Psychological interventions for anxiety and depression in CHD patients have demonstrated small and uncertain effects of symptoms, and no effect on cardiovascular outcomes. Therefore, testing the effectiveness of specific psychological interventions that may affect central mechanisms for cardiovascular outcomes, has been requested. The Attention training (ATT) Study is a randomized controlled trial comparing group-attention training to wait-list control in 64 patients who experience significant anxiety and depression after a CHD event. It will also be explored whether reduction in psychological symptoms is correlated with changes in biological markers with a potential link to cardiovascular outcomes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Attention Training Techniqe | Experimental | The treatment manual will consist of up to six weekly group sessions with 45-90 minutes duration. |
|
| Wait-list control | No Intervention | The wait-list control condition will not receive any psychological intervention during the six weeks waiting period. Subsequently, this group will also receive the intervention if the study entry criteria is still fulfilled |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Attention Training Technique | Behavioral | Attention Training Technique is a six weeks psychological intervention provided by trained professionals |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Hospital Anxiety and Depression -anxiety subscale score and Hospital Anxiety and Depression -depression subscale score | Changes in Hospital Anxiety and Depression -anxiety subscale score and Hospital Anxiety and Depression -depression subscale scores within and between the two treatment arms. Scores range 0-21, higher scores indicate more symptoms | Up to six weeks and six months after randomization |
| Differences in proportion with Hospital Anxiety and Depression -anxiety and Hospital Anxiety and Depression-depression subscale scores <8 | Differences in proportion with Hospital Anxiety and Depression -anxiety subscale and Hospital Anxiety and Depression -depression subscale scores <8 within and between the two treatment arms. Scores >=8 indicate signicant symptoms | Up to six weeks and six months after randomization |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in rumination scores | Changes in rumination scores assessed by the Ruminative Response scale within and between the two treatment arms. Scores range from 22-88, higher scores indicate more symptoms | Up to six weeks and six months after randomization |
| Changes in worry scores |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| John Munkhaugen, MD,PhD | Contact | +4797524194 | johmun@vestreviken.no | |
| Toril Dammen, MD,PhD | Contact | +4790163433 | toril.dammen@medisin.uio.no |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital of Vestfold | Not yet recruiting | Tønsberg | Vestfold and Telemark County | 3103 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40461992 | Derived | Tunheim K, Papageorgiou C, Lie HC, Munkhaugen J, Dammen T. Experiences of the attention training technique delivered in groups as treatment for anxiety and depression in patients with coronary heart disease: a qualitative study. BMC Psychiatry. 2025 Jun 3;25(1):573. doi: 10.1186/s12888-025-07027-4. | |
| 37790218 | Derived |
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| ID | Term |
|---|---|
| D003863 | Depression |
| D001008 | Anxiety Disorders |
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D001523 | Mental Disorders |
| D003327 | Coronary Disease |
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Changes in worry scores assessed by the Penn State Worry Questionnaire within and between the two treatment arms. Scores range 16-80, higher scores indicate more symptoms |
| Up to six weeks and six months after randomization |
| Changes in Positive Beliefs about Rumination Scale scores | Changes in Positive Beliefs about Rumination scores assessed by the Positive Beliefs about Rumination Questionnaire within and between the two treatment arms. Scores range 9-36, higher scores indicate stronger beliefs | Up to six weeks and six months after randomization |
| Changes in Negative Beliefs about Rumination Scale scores | Changes in Negative Beliefs about Rumination scores assessed by the Negative Beliefs about Rumination Questionnaire within and between the two treatment arms. Scores range 13-52, higher scores indicate stronger beliefs | Up to six weeks and six months after randomization |
| Changes in Metacognitions Questionnaire-30 scores | Changes in Metacognitions assessed by the Metacognitions Questionnaire-30 within and between the two treatment arms. Scores range 0-21, higher scores indicate more symptoms . Scores range 30-120, higher scores indicate stronger beliefs | Up to six weeks and six months after randomization |
| Changes in type d personality and its traits negative affectivity and social inhibition | Changes in type d personality and its traits negative affectivity and social inhibition assessed by the Distressed Scale (DS)-14 within and between the two treatment arms. Scores range 0-28, higher scores indicate more symptoms | Up to six weeks and six months after randomization |
| Changes in quality of life | Changes in quality of life assessed by the Short Form (SF) 12 within and between the two treatment arms. Scores range 1-100, lower scores indicate lower quality of life | Up to six weeks and six months after randomization |
| Changes in Bergen Insomnia Scale scores | Changes in Bergen Insomnia Scale scores assessed by the Bergen Insomnia Scale within and between the two treatment arms. Scores range 0-42, higher scores indicate more symptoms | Up to six weeks and six months after randomization |
| Changes in C-reactive Protein (CRP) | Changes in C-reactive Protein (CRP) measured in blood within and between the two treatment arms. Values range 0 to >20, higher values indicate more subclinical inflammation | Up to six weeks and six months after randomization |
| Vestre Viken Trust Drammen hospital | Recruiting | Drammen | Viken County | 3004 | Norway |
|
| Dammen T, Tunheim K, Munkhaugen J, Klungsoyr O, Papageorgiou C. Attention training technique delivered in groups as treatment for anxiety and depression in patients with coronary heart disease: study protocol for a waiting-list randomized controlled trial. Front Psychol. 2023 Sep 18;14:1226539. doi: 10.3389/fpsyg.2023.1226539. eCollection 2023. |
| D017202 |
| Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |