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| Name | Class |
|---|---|
| Belgian Federal Public Service, Food Chain Safety and Environment | OTHER_GOV |
| Centre Hospitalier Universitaire Saint Pierre | OTHER |
| AZ Sint-Jan AV | OTHER |
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The Belgian Severe Acute Respiratory Infections network (BELSARI-net) was implemented during the influenza season 2011-2012 following the recommendations of the World Health Organization (WHO) to monitor severity of influenza viruses in hospitals. The network is composed of 6 hospitals throughout the country, two in each administrative region (Flanders, Wallonia and Brussels-Capital), and operates during the influenza epidemic period (from the last week of December or first/second week of January to the third/last week of April, depending on when influenza virus circulation is detected by the general population, based on the Influenza-like illness (ILI) network of general practitioners).
Enrollment is performed for all cases matching the SARI case definition (based on WHO's case definition) and accepting to take part. A respiratory specimen is sampled systematically from each participant, and detailed clinico-epidemiological data, such as information on age, sex, symptoms and potential risk factors such as pregnancy or comorbidities (chronic respiratory diseases, asthma, chronic cardiovascular diseases, renal insufficiency, obesity, diabetes, hepatic or renal insufficiency, immunodeficiency, neuromuscular disease, pregnancy) is also collected. Participants are followed up during hospitalization for the occurrence of complications (detection of pneumonia based on chest radiography, development of acute respiratory distress syndrome (ARDS), requirement for respiratory assistance and/or for extracorporeal membrane oxygenation (ECMO), admission in intensive care unit (ICU)), or death (all-cause death).
The current project includes all the samples received by the Belgian National Influenza Centre (NIC) during the influenza seasons 2011-2012 till 2019-2020.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SARI case |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| respiratory specimen | Diagnostic Test | nasopharyngeal swab or nasal aspiration or broncho-alveolar lavage |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants positive for influenza viruses | result of influenza PCR detection test (typing and subtyping) | within 10 days after symptom onset |
| Number of participants positive for non-influenza viruses | results of non-influenza multiplex PCR detection test (16 targets) | within 10 days after symptom onset (only routinely tested since influenza season 2015-2016) |
| Number of participants who died during hospitalization | alive or dead | from date of hospital admission until date of death during hospitalization or date of hospital exit |
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with at least one known risk factor | existence of co-morbidities or known risk factors among a list provided on form | on date of hospital admission |
| Number of participants who experienced at least one complication |
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Inclusion Criteria:
Exclusion Criteria:
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Patients admitted to one of the 6 participating hospital during the season surveillance dates.
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34558405 | Result | Subissi L, Bossuyt N, Reynders M, Gerard M, Dauby N, Lacor P, Daelemans S, Lissoir B, Holemans X, Magerman K, Jouck D, Bourgeois M, Delaere B, Quoilin S, Van Gucht S, Thomas I, Barbezange C. Spotlight influenza: Extending influenza surveillance to detect non-influenza respiratory viruses of public health relevance: analysis of surveillance data, Belgium, 2015 to 2019. Euro Surveill. 2021 Sep;26(38):2001104. doi: 10.2807/1560-7917.ES.2021.26.38.2001104. | |
| 33937883 |
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| ID | Term |
|---|---|
| D056152 | Respiratory Rate |
| ID | Term |
|---|---|
| D055986 | Vital Signs |
| D010808 | Physical Examination |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| Universitair Ziekenhuis Brussel |
| OTHER |
| Grand Hôpital de Charleroi | OTHER |
| Jessa Hospital | OTHER |
| Centre Hospitalier Universitaire UCLouvain Namur | OTHER |
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respiratory specimens (mainly nasopharyngeal swabs, but a few nasal aspirates and broncho-alveolar lavages)
occurence of complications (among a list provided on form) during hospitalisation stay
| from date of hospital admission until date of death during hospitalization or date of hospital exit |
| Result |
| Fischer N, Dauby N, Bossuyt N, Reynders M, Gerard M, Lacor P, Daelemans S, Lissoir B, Holemans X, Magerman K, Jouck D, Bourgeois M, Delaere B, Quoilin S, Van Gucht S, Thomas I, Barbezange C, Subissi L. Monitoring of human coronaviruses in Belgian primary care and hospitals, 2015-20: a surveillance study. Lancet Microbe. 2021 Mar;2(3):e105-e114. doi: 10.1016/S2666-5247(20)30221-4. Epub 2021 Jan 27. |
| 33006303 | Result | Subissi L, Bossuyt N, Reynders M, Gerard M, Dauby N, Bourgeois M, Delaere B, Quoilin S, Van Gucht S, Thomas I, Barbezange C. Capturing respiratory syncytial virus season in Belgium using the influenza severe acute respiratory infection surveillance network, season 2018/19. Euro Surveill. 2020 Oct;25(39):1900627. doi: 10.2807/1560-7917.ES.2020.25.39.1900627. |
| 37470740 | Result | Fischer N, Moreels S, Dauby N, Reynders M, Petit E, Gerard M, Lacor P, Daelemans S, Lissoir B, Holemans X, Magerman K, Jouck D, Bourgeois M, Delaere B, Quoilin S, Van Gucht S, Thomas I, Bossuyt N, Barbezange C. Influenza versus other respiratory viruses - assessing severity among hospitalised children, Belgium, 2011 to 2020. Euro Surveill. 2023 Jul;28(29):2300056. doi: 10.2807/1560-7917.ES.2023.28.29.2300056. |
| D012119 |
| Respiration |
| D012143 | Respiratory Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |