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The present prospective clinical study will be undertaken for assessment of the effect of application of i-PRF on the rate of levelling and alignment, molar distalization& intrusion of anterior teeth in deep bite cases
Assessment of the effect of application of i-PRF on the rate of levelling and alignment, molar distalization& intrusion of anterior teeth in deep bite cases
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group I | Experimental | Intervention side: application of i-PRF with distalization of maxillary first molar that will be performed on intervention sides according to a standardized protocol. |
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| Group II | No Intervention | Control side: distalization of maxillary first molar that will be performed without any intervention | |
| Group A | Experimental | levelling and alignment assisted with Injectable Platelet-rich fibrin (i-PRF) according to a standardized protocol. |
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| Group B | No Intervention | leveling and alignment will be commenced without Injection of Injectable platelet-rich fibrin (i-PRF) | |
| Group a | Experimental | Will includes 9 patients who will receive intrusive arch after leveling and alignment assisted Injectable Platelet-rich fibrin (i-PRF) according to a standardized protocol. |
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| Group b |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| injectable platelet rich fibrin | Biological | injectable platelet rich fibrin |
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| Measure | Description | Time Frame |
|---|---|---|
| effect of injectable platelet rich fibrin on different tooth movements | rate of tooth movement | post interventional at 4 months |
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Inclusion Criteria:An age range from 15-22 years. Severe crowding or protrusion requiring 1st premolars extractions followed by symmetrical canine retraction.
All permanent teeth present, 3rd molars are excluded. Good oral and general health. No systemic disease/medication that could interfere with orthodontic tooth movement. No previous orthodontic treatment.
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Exclusion Criteria:Patient diagnosed to have an indication for non-extraction approach.
Poor oral hygiene or periodontally compromised patient. Patient with craniofacial anomalies or previous history of trauma, bruxism or parafunctions.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| AlAzhar university | Cairo | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33481053 | Background | Zeitounlouian TS, Zeno KG, Brad BA, Haddad RA. Effect of injectable platelet-rich fibrin (i-PRF) in accelerating orthodontic tooth movement : A randomized split-mouth-controlled trial. J Orofac Orthop. 2021 Jul;82(4):268-277. doi: 10.1007/s00056-020-00275-x. Epub 2021 Jan 22. | |
| 33459765 | Background | Erdur EA, Karakasli K, Oncu E, Ozturk B, Hakki S. Effect of injectable platelet-rich fibrin (i-PRF) on the rate of tooth movement. Angle Orthod. 2021 May 1;91(3):285-292. doi: 10.2319/060320-508.1. |
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Factorial Assignment
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Will includes 9 patients who will receive intrusive utility arches after leveling and alignment without Injection of Injectable platelet-rich fibrin (i-PRF) |