Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
In a randomized, triple-blind, sham-controlled clinical trial, we will assess the effect of a single session frontal cortex High-Definition transcranial Direct Current Stimulation (HD-tDCS) on brain activity and functional connectivity underlying the behavioral change in attentional control in healthy participants. Participants will be recruited after meeting the inclusion criteria and will be randomly assigned to active or sham stimulation groups. All participants will undergo resting-state functional Magnetic Resonance Imaging (rsfMRI) scan and perform an Attention Network Test (ANT) in a functional Magnetic Resonance Imaging (fMRI) scanner before and after receiving a single session of active or sham HD-tDCS.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active HD-tDCS | Experimental | Participants in the active arm will receive 20 min of real High-Definition transcranial direct current stimulation. Additional ramp-up and ramp-down phases at the beginning and the end of stimulation will last for 30 s. |
|
| Sham HD-tDCS | Experimental | During the sham session, the montage will be identical, however, the current amplitude will ramp up for 30 seconds, and for the remaining stimulation time, the current flow will terminate and will be kept to zero. Ramp-down phase at the end of stimulation will last for 30 s. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Active High-Definition Transcranial Direct Current Stimulation (HD-tDCS) | Device | Portable multi-channel tES stimulation (Starstim 8, Neuroelectric, Barcelona, Spain) will be used. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Attention Network Test (ANT) performance before and after the intervention (active versus sham HD-tDCS) | Immediate before and immediate after intervention | |
| Change in resting state functional connectivity before and after the intervention (active versus sham HD-tDCS) | Immediate before and immediate after intervention | |
| Change in task-based functional connectivity during Attention Network Test (ANT) before and after the intervention (active versus sham HD-tDCS) | Immediate before and immediate after intervention | |
| Change in the blood-oxygen-level-dependent (BOLD) signal during Attention Network Test (ANT) before and after the intervention (active versus sham HD-tDCS) | Immediate before and immediate after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Side effect checklist for transcranial Direct Current Stimulation (Reported as Yes or No) | One day after simulation session |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Faculty of Psychology | Contact | +982188259378 | psyedu@ut.ac.ir |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Psychology | Recruiting | Tehran | 1445983861 | Iran |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Participants are allocated to one of two conditions: Active or Sham.
Not provided
Not provided
Triple-blind study
| Sham High-Definition Transcranial Direct Current Stimulation (HD-tDCS) | Device | Portable multi-channel tES stimulation (Starstim 8, Neuroelectric, Barcelona, Spain) will be used. |
|