The clinical benefits of endovascular treatment in renal artery stenosis remain controversial. This study uses arterial spin labelling MRI and flat-panel detector parenchymal blood volume imaging to observe the change in renal perfusion after endovascular treatment in renal artery stenosis.

Inclusion Criteria:

• patients who provided informed consent
• patients who were diagnosed with RAS by CTA, MRA, or Doppler ultrasonography
• patients who were aged 18 years or older
• patients whose intervened renal arteries were not completely occluded (confirmed by DSA)
• the stenosis percentage exceeding 70%
• patients who had uncontrolled blood pressure or impaired renal function
• paitents whose affected kidney did not have total loss of function

Exclusion Criteria:

• were pregnant
• had a history of renal transplantation or renal artery bypass surgery
• were allergic to iodine contrast medium
• had other contraindications of endovascular treatment
• contraindications of MRI examinations
• had technical failure in the endovascular treatment.

The study was conducted in renal artery stenosis patients aged 18 to 80 years with uncontrolled blood pressure or impaired renal function, who were intended for endovascular treatment. CTA, MRA, or Doppler ultrasonography were used for the assessment of the stenosis percentage of renal artery. Subjects with technical failure were excluded in order to reduce the influence of other variables.