Detection of Microplastics in Cardiac Surgery Patients

Detection of Microplastics in Cardiac Surgery Patients: Its Metabolic Pathways and Toxic Effects

The exponential growth in plastic production/use translates into a parallel increase in environmental plastic waste, which is constantly degraded into microplastics and nanoplastics. Information on the effects of microplastics on human health is still preliminary.

Cardiac surgery patients is a population high exposed to plastics. This observational study will obtain biological samples of cardiac surgery patients as a reference and vulnerable group of individuals highly exposed to microplastics and potentially more susceptible.

The objective of this research is to be able to detect microplastics on blood and operation samples of cardiac surgery patients as well as their potential genotoxic and immunological damage.

Inclusion Criteria:

• Age ≥18 years
• Elective cardiac surgery

Exclusion Criteria:

• Emergency surgery or limited-term surgery
• Previous cardiac surgery
• Previous severe liver disease
• Pregnant or planning to become pregnant
• Have a malignant tumor