Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
As the posterior lumbosacral spine fixation surgeries are common spine procedures done nowadays due to different causes and as this spine procedure is mostly accompanied with moderate to severe postoperative pain, so it is necessary to find an effective and efficient postoperative analgesia for patients with this surgery.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dexmedetomidine combined with bupivacaine group (DB group) | Active Comparator | patients received 1ug/kg dexmedetomidine plus 20 mL of bupivacaine 0.25%, |
|
| bupivacaine 0.25%, | Active Comparator | patients received 20 ml of bupivacaine 0.25% |
|
| control group (S group) | Placebo Comparator | patients received 20 ml of normal saline 0.9%. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexmedetomidine injection | Drug | 1ug/kg dexmedetomidine plus 20 mL of bupivacaine 0.25% |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative visual analogue scale (VAS) | The visual analog scale (VAS) is a simple and often used method for evaluating variations in pain intensity. | the first 24 hours postoperative |
| Amount of post operative opioid consumption for the first 24 hours | Amount of total opioid consumption for 24 hours postoperative | the first 24 hours postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative visual analogue scale (VAS) | The visual analog scale (VAS) is a simple and often used method for evaluating variations in pain intensity. | the second 24 hour postoperative |
| Amount of post operative opioid consumption for the second 24 hours |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Abdelmaksod Mohammed M Mousa, MD | October 6 University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| October 6 university hospital | Giza | 12573 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38344257 | Derived | Abu El Hassan SHA, Wahsh EA, Mousa AM, Ibrahim ARN, Mohammed EL. Comparative Study Between Dexmedetomidine with Bupivacaine and Bupivacaine Alone in Erector Spinae Plane Block for Postoperative Pain Control of Posterior Lumbosacral Spine Fixation Surgeries: A Randomized Controlled Trial. Drug Des Devel Ther. 2024 Feb 7;18:351-363. doi: 10.2147/DDDT.S444485. eCollection 2024. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D020927 | Dexmedetomidine |
| D002045 | Bupivacaine |
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Bupivacaine 0.25% Injectable Solution | Drug | 20 ml of bupivacaine 0.25%, |
|
| normal saline | Drug | 20 ml of normal saline 0.9%. |
|
Amount of total opioid consumption for the second 24 hours postoperative |
| the second 24 hour postoperative |
| D000813 |
| Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |