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The investigator would like to investigate the impact of theta-burst stimulation over cerebellum in adults with autism spectrum disorder
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active | Experimental | All of the participants will accept one session iTBS over right Crus I/II. The total pulses of every session are 1200 pulses (600 pulses with 15 minutes interval) *iTBS = intermittent theta burst stimulation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| intermittent theta burst stimulation | Device | stimulatory protocol |
|
| Measure | Description | Time Frame |
|---|---|---|
| Adverse effects report form (Headache) | Recording adverse effects in participants after iTBS. | 1 week after iTBS (post iTBS) |
| Adverse effects report form (Dizziness) | Recording adverse effects in participants after iTBS. | 1 week after iTBS (post iTBS) |
| Adverse effects report form (Tinnitus) | Recording adverse effects in participants after iTBS. | 1 week after iTBS (post iTBS) |
| Adverse effects report form (Seizure) | Recording adverse effects in participants after iTBS. | 1 week after iTBS (post iTBS) |
| Adverse effects report form (Other) | Recording adverse effects in participants after iTBS. | 1 week after iTBS (post iTBS) |
| Measure | Description | Time Frame |
|---|---|---|
| MRI T1 | Brain structural volumes (cm²) | Within one month |
| functional MRI (resting-state/biological motion task) - BOLD signal | Blood-oxygen-level-dependent (BOLD) signal is a measurement used in fMRI, which reflects the neural activity. |
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Inclusion Criteria:
Exclusion Criteria:
Withdrawal criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chang Gung Memorial Hospital | Taoyuan | Taiwan |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Jun 1, 2025 | |
| Reset | Jun 13, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jun 1, 2025 | Jun 13, 2025 |
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| ID | Term |
|---|---|
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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| Within one month |