Does an Acute Exercise Bout Increases Soluble and Muscle Myokine Concentration in Healthy, Older Persons
Does an Acute Exercise Bout Increases Soluble and Muscle Myokine Concentration in Healthy, Older Persons
The incidence of age-related diseases, such as cancer and cardiovascular diseases, rapidly rises. These days, age-related diseases cause the majority of all healthcare expenses. During ageing senescent cells secrete a range of harmful inflammatory signals, which leads to chronic inflammation (inflamm-aging) and accelerates aging throughout the rest of the body. Interestingly, people who regularly exercise show less signs of inflamm-aging compared to people with a sedentary lifestyle. Molecules secreted by skeletal muscles, called myokines, may play an important role. However, the underlying molecular mechanisms remain unknown. This pilot study aims to investigate if an acute bout of resistance training is an appropriate tool to induce an increase in the release of muscle derived myokines in aged persons.
Inclusion Criteria:
Exclusion Criteria:
Smoking
Infection < 2 weeks ago
Received a vaccine < 2 weeks ago
Allergy to Lidocain
Immune deficiency
Presence of a tumour or in treatment
Usage of anti-coagulant medication
Presence of following conditions:
bert.opteijnde@uhasselt.be+3211292121
chiel.hex@uhasselt.be