Acceleration of Orthodontic Tooth Movement

Evaluation of Clinical Efficacy of Locally Injected Vitamin D3 (Calcitriol or 1,25 Dihidroxicolecalciferol) in Accelerating Orthodontic Tooth Movement (A Randomized Controlled Trial)

EVALUATION OF EFFICACY OF LOCALLY INJECTED Vitamin D3 (calcitriol or 1.25 dihidroxicolecalciferol) IN ACCELERATING ORTHODONTIC MOVEMENT Design: A randomized, controlled, crossover, double-blind clinical study including Eighteen adult , aged 15-25 years old.

The rate of orthodontic tooth movement depends on two general factors: the forces used in order to cause orthodontic tooth movement and respectively the individual (biological) response of the body to these forces.

There are many methods for accelerating orthodontic tooth movement. but, every method has its disadvantages, such as pain and root absorption. Locally injected of vitamin d3 was proposed to accelerates tooth movement with minimal disadvantages, but there aren't enough clinical studies to prove this claim.

Inclusion Criteria:

• Mild to moderate crowding of mandible teeth. In accordance with LITTLE'S IRREGULARITY INDEX
• Healthy patient
• No previous orthodontic treatment
• Vital teeth with periodental tissue without root absorption,

Exclusion Criteria:

• Previous history of orthodontic or orthopedic treatment.
• Presence of craniofacial anomalies.
• Presence of any signs and symptoms of gingival and periodontal diseases.
• Presence of significant medical history (including drug allergy).
• Pregnant and lactating women.