Botulinum Toxin Injection in Reducing Lip Scar Following Cleft Lip Repair

Evaluation of Botulinum Toxin Injection in Reducing Lip Scar Following Cleft Lip Repair (Randomized Controlled Clinical Trial)

A cleft lip is a congenital defect resulting from failing to merge developmental processes in the Orofacial region. One of the most common complications surgeons fear after cleft lip repair is a hypertrophic scar. A cleft scar negatively affects a patient's appearance, psychology, and function. Several techniques have been proposed to improve lip scars such as steroid therapy, laser therapy, and silica gel. Despite such efforts, the results were still unsatisfactory. Botulinum Toxin injections may provide a more reliable method

Inclusion Criteria:

• With mild to severe cleft lip deformity requiring repair.
• Neonates up to 1 year of age.
• Patients with or without cleft palate.
• Systemically healthy patients.
• Patients follow postoperative instructions provided by their legal guardians.

Exclusion Criteria:

• Patients with a syndromic type of cleft lip.
• Patients suffering from relevant systemic and metabolic diseases.
• Patients suffering from immunosuppressive diseases.
• Patients suffering from neuromuscular disorders like Myasthenia Gravis.
• Patients with special needs.