Hypotension After Anesthetic Induction with Remimazolam in Elderly

Comparison of the Incidence of Hypotension with Bolus Versus Continuous Remimazolam for Anesthetic Induction in Elderly Patients

Even though remimazolam is known to be safely administered without hemodynamic instability, hypotension is the one of the common side effects of remimazolam. Because elderly patients are susceptible to hypotension due to old age, multimodality, and multiple medications, hypotension can be harmful in elderly patients. Remimazolam can be administered either bolus or continuous for anesthetic induction. In our study the investigators aimed to compare the incidence of hypotension after anesthetic induction using remimazolam by bolus injection and continuous infusion in elderly patients.

Inclusion Criteria:

• Elderly patients with age over 60 years old
• scheduled for elective surgery under general anesthesia
• American Society of Anesthesiology Physical Status I-III

Exclusion Criteria:

• Arrhythmia
• Liver dysfunction
• Kidney dysfunction
• Uncontrolled hypertension
• Uncontrolled diabetes mellitus
• Allergic to benzodiazepines
• Heart failure
• Drug intoxication
• Alcoholics
• Cognitive dysfunction
• Unable to understand and consent voluntarily