Perio Treatment & Cerebrovascular Function

Impact of Periodontal Treatment on Brain Hemodynamics

Periodontitis has been linked to increased risk of cerebrovascular disease. Impaired brain hemodynamics has been suggested as early markers of cerebral macro and microangiopathy. Therefore, the aim of this clinical trial will be to assess the potential effect of periodontal treatment on cerebral hemodynamics in otherwise healthy patients with severe periodontitis over 6 months.

Inclusion Criteria:

• Otherwise healthy subjects with severe periodontitis.

Exclusion Criteria:

• <10 teeth
• current smokers
• undergo periodontal treatment within the last 6 months.
• receive antibiotics or anti-inflammatory drugs within the last 3 months.