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| Name | Class |
|---|---|
| DLR German Aerospace Center | OTHER |
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The aim of this study is to investigate the influence of four different ambient temperatures (18, 22, 28, 38°C) on the resting energy expenditure of healthy adults by respiratory gas analysis. It is assumed that the resting energy expenditure is higher at 18°C and 38°C than at the temperatures in between.
In a crossover-design, 32 healthy men and women participate in four interventions. Each intervention includes a measurement of the resting energy expenditure by respiratory gas analysis at a different ambient temperature (18,22, 28 and 38°C). During this time body core- and surface temperature are assessed, as well as body composition via bioelectrical impedance analysis. For each participant the four individual study days take place in a randomized order on consecutive weekdays within a week.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cold temperature | Experimental | 18°C |
|
| Room temperature | Experimental | 22°C |
|
| Thermoneutral temperature | Experimental | 28°C |
|
| Hot temperature | Experimental | 38°C |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Respiratory analysis at cold temperature | Other | Respiratory analysis at an ambient temperature of 18°C |
|
| Measure | Description | Time Frame |
|---|---|---|
| Resting Energy Expenditure | Volume of inhaled oxygen (VO2) in L/min and exhaled carbon dioxide (VCO2) in L/min | 20 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Body core temperature | Body core temperature: assessed every ten seconds during respiratory analysis (°C) | 20 minutes |
| Body surface temperature | Body surface temperature: assessed every ten seconds during respiratory analysis (°C) |
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Inclusion Criteria
Exclusion Criteria
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| Name | Affiliation | Role |
|---|---|---|
| Sarah Egert, Prof. PhD | University of Bonn | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Bonn | Bonn | 53115 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39814140 | Derived | Henkel S, Frings-Meuthen P, Diekmann C, Coenen M, Stoffel-Wagner B, Nemeth R, Pesta D, Egert S. Influence of Ambient Temperature on Resting Energy Expenditure in Metabolically Healthy Males and Females. J Nutr. 2025 Mar;155(3):862-870. doi: 10.1016/j.tjnut.2025.01.013. Epub 2025 Jan 13. |
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| Respiratory analysis at room temperature | Other | Respiratory analysis at an ambient temperature of 22°C |
|
| Respiratory analysis at thermoneutral temperature | Other | Respiratory analysis at an ambient temperature of 28°C |
|
| Respiratory analysis at hot temperature | Other | Respiratory analysis at an ambient temperature of 38°C |
|
| 20 minutes |
| Body composition | assessed daily via bioelectrical impedance analysis after respiratory analysis (FFM (kg), FM (kg)) | 5 minutes (after respiratory analysis) |
| Blood pressure | assessed daily before respiratory analysis (mmHg) | 10 minutes (at beginning of study day) |