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| Name | Class |
|---|---|
| Glico Asia Pacific Pte Ltd | UNKNOWN |
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Food is emerging as the new medicine. There has been growing evidence of the beneficial effects of foods, including nuts on human health. Modulation of both glucose and insulin are at the heart of reducing the risk of cardiovascular and other metabolic diseases. The contribution that nuts have on human health has been studied extensively and it is well established that the consumption of nuts revealed improvements in both blood glucose profile and reduced the risk of coronary heart diseases. Nuts, such as almonds, are nutrient-dense foods that are particularly rich in a-tocopherol. They are excellent sources of protein (~25% of energy) and fibre, low in saturated fatty acid content (4-6%) and high in monounsaturated fatty acids. They also contain significant amounts of essential micronutrients such as folate (B vitamin) and polyphenols. Recently, strong interests on the health effects of nuts improving metabolic syndrome and controlling diabetes has been reported. Preliminary studies have indicated that the inclusion of nuts in the diets of individuals with diabetes and/or metabolic syndrome may improve postprandial glycaemic response, and lipid metabolism in the long run.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control: Glucose | Other | 50 g glucose dissolved in 250 mL water |
|
| Control: Bread | Other | 91.4 g white bread |
|
| Bread and Almond paste | Experimental | 88.7 g white bread and 15 g almond paste |
|
| Bread, Almond paste and Inulin | Experimental | 88.7 g white bread, 15 g almond paste and 4 g inulin |
|
| Bread, Low dose almond paste and Inulin | Experimental | 89.6 g white bread, 10 g almond paste and 3.8 g inulin |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Glucose control | Other | 50 g glucose dissolved in 250 mL water |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial glucose response | 0, 15, 30, 45, 60, 90, 120, 150, 180 minutes | |
| Postprandial insulin response | 0, 15, 30, 45, 60, 90, 120, 150, 180 minutes | |
| GI calculation for the composite meal | 0, 15, 30, 45, 60, 90, 120, 150, 180 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial low-density lipoprotein cholesterol (LDL) level | 0, 15, 30, 45, 60, 90, 120, 150, 180 minutes | |
| Postprandial high-density lipoprotein cholesterol (HDL) level | 0, 15, 30, 45, 60, 90, 120, 150, 180 minutes |
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Inclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Nutrition Research Centre | Singapore | 117599 | Singapore |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36329602 | Derived | Bi X, Yeo MTY, Jeyakumar Henry C. Almond paste and dietary fibre: a novel way to improve postprandial glucose and lipid profiles? Int J Food Sci Nutr. 2022 Dec;73(8):1124-1131. doi: 10.1080/09637486.2022.2141207. Epub 2022 Nov 3. |
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| Bread control |
| Other |
91.4 g white bread |
|
| Almond paste | Other | 88.7 g white bread and 15 g almond paste |
|
| Almond paste and inulin | Other | 88.7 g white bread, 15 g almond paste and 4 g inulin |
|
| Low dose almond paste and inulin | Other | 89.6 g white bread, 10 g almond paste and 3.8 g inulin |
|
| Postprandial total cholesterol (TC) level | 0, 15, 30, 45, 60, 90, 120, 150, 180 minutes |
| Postprandial triglyceride level | 0, 15, 30, 45, 60, 90, 120, 150, 180 minutes |
| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
| D008659 | Metabolic Diseases |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D000085002 | Glycemic Control |
| D007444 | Inulin |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
| D013213 | Starch |
| D005936 | Glucans |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
| D004040 | Dietary Carbohydrates |
| D002241 | Carbohydrates |
| D005630 | Fructans |
| D011134 | Polysaccharides |
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