Common and Specific Information From Neuroimaging and Smartphone

Individual Gait Pattern and MRI Lesion Load to Quantify Gait Impairment in MS: A Cross Sectional Study.

Gait alteration is frequent in MS and limitation in walking ability is a major concern in MS patients. Umanit and LMJL (Nantes university) has developed a device call egait to assess walking ability in individuals (eg MS patients).

This device consists in a commercialized IMU sensor (MetaMotionR Sensor, Mbientilab) worn at the right hip, a smartphone app and dedicated algorithm/mathematical model to extract raw sensor data and calculate individual gait pattern (IGP). This IGP consists of a curve, based on quaternion and representing the rotation recorded by the IMU during an average gait cycle. Pursue previous works conducted on (IGP to assess) gait alteration in MS by adding (to IGP) new information from MRI.

Inclusion Criteria :

• Diagnosis of MS based on McDonald criteria (including Relapsing-remitting and progressive MS)
• Over 18 years old /age greater than 18 years
• Patients followed at Nantes university hospital or Rennes university hospital
• Last known EDSS before inclusion ranging from 0 to 6 inclusive/EDSS of 0 to 6 inclusive, prior inclusion
• No relapse within 3 months
• With a Medullar MRI planed as part as usual care
• MRI scan can be performed within a maximum of 4 months after or before the walking test.
• Affiliated person or beneficiary of a social security scheme

Exclusion Criteria :

• Bilateral aid needed to walk
• Women who are pregnant
• Patient having expressed their opposition
• Patient under guardianship or security measure