Quantifying Gait Alteration in Multiple Sclerosis Using a Wearable Device

Uncontrolled, Single-center Study to Quantify Gait Disturbance in Patients With Multiple Sclerosis

Gait alteration is frequent in MS and limitation in walking ability is a major concern in MS patients. The development of wearable device offers the opportunity to collect data during daily activity including walking.

Umanit and LMJ (Nantes university) has developed a device call eMSgait to assess walking ability in MS patients individuals (eg MS patients). This device consists in a commercialized IMU sensor (MetaMotionR Sensor, Mbientilab) worn at the right hip, a smartphone app and dedicated algorithm/mathematical model to extract raw sensor data and calculate individual gait pattern (IGP). This IGP consists of a curve, based on quaternion and representing the rotation recorded by the IMU during an average gait cycle. Pursue first pilot work assessing information from IGP on gait alteration in MS.

Inclusion Criteria:

• Age 18 - 64 years
• Diagnosis of MS based on McDonald criteria (including Relapsing-remitting and progressive MS)
• No relapse within the last 5 weeks before recruitment
• Able to walk with or without assistance/help/aid (one or 2 canes)
• EDSS [0-6]

Exclusion Criteria:

• Women who are pregnant
• Patient having expressed their opposition
• Patient under guardianship or security measure