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| Name | Class |
|---|---|
| University of Amsterdam | OTHER |
| Universita di Verona | OTHER |
| Umberto I Mauriziano Hospital Turin | UNKNOWN |
| IRCCS Azienda Ospedaliero-Universitaria di Bologna |
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The use of a simultaneous resection in patients with synchronous colorectal liver metastases has increased over the past decades. However, it remains unclear when a simultaneous resection is beneficial and when it should be avoided. The objective of this retrospective study is therefore to compare the outcomes of a simultaneous resection for synchronous colorectal liver metastases in different settings, and to assess which factors are independently associated with unfavorable outcomes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Minor liver resection | Minor liver resection (<3 contiguous segments) in the anterolateral segments | ||
| Technically major liver resection | Minor liver resection (<3 contiguous segments) in the posterosuperior segments (Segment 1,4a,7,8) |
| |
| Major liver resection | Major liver resection (3 or more contiguous segments) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Major liver resection | Procedure | Major liver resection (3 or more contiguous segments) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Major complications | Severe complications (Clavien-Dindo grade 3a or higher) related to the surgical procedure | 30 days postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Overall complications | Overall complications related to the surgical procedure | 30 days postoperatively |
| Length of hospital stay | The length of hospital stay for the surgical procedure |
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Inclusion Criteria:
Exclusion Criteria:
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Patients that underwent an elective minimally invasive or open simultaneous resection of colorectal cancer and synchronous colorectal liver metastases in 17 hepato-biliary referall centers in the time period from January 2004 to December 2019
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fondazione Poliambulanza Istituto Ospedaliero | Brescia | Lombardy | 25124 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37093069 | Derived | Sijberden JP, Zimmitti G, Conci S, Russolillo N, Masetti M, Cipriani F, Lanari J, Gorgec B, Benedetti Cacciaguerra A, Rotellar F, D'Hondt M, Edwin B, Sutcliffe RP, Dagher I, Efanov M, Lopez-Ben S, Primrose JN, Giuliante F, Spinelli A, Chand M, Alvarez S, Langella S, Nicosia S, Ruzzenente A, Vivarelli M, Cillo U, Aldrighetti L, Jovine E, Ferrero A, Guglielmi A, Besselink MG, Abu Hilal M. Simultaneous resection of colorectal cancer and synchronous liver metastases: what determines the risk of unfavorable outcomes? An international multicenter retrospective cohort study. Int J Surg. 2023 Mar 1;109(3):244-254. doi: 10.1097/JS9.0000000000000068. |
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The data of this study will be available from the corresponding author, Professor Mohammed Abu Hilal, upon reasonable request. The data are not publicly available since this could compromise the privacy of research participants.
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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| OTHER |
| IRCCS San Raffaele | OTHER |
| University Hospital Padua | UNKNOWN |
| Riuniti Hospital Polytechnic University of Marche Ancona | UNKNOWN |
| Clinica Universidad de Navarra Pamplona | UNKNOWN |
| Groeninge Hospital Kortrijk | UNKNOWN |
| Oslo University Hospital and Institute of Medicine | UNKNOWN |
| The Queen Elizabeth Hospital | OTHER |
| Antoine Béclère Hospital Paris | UNKNOWN |
| Moscow Clinical Research Centre | UNKNOWN |
| University Hospital of Girona Dr. Josep Trueta | NETWORK |
| University Hospital Southampton NHS Foundation Trust | OTHER |
| Catholic University of the Sacred Heart | OTHER |
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| Technically major liver resection | Procedure | Minor liver resection (<3 contiguous segments) in the posterosuperior segments (segment 1,4a,7,8) |
|
| 30 days postoperatively |
| R0 resection margin | Proportion of patients in whom a microscopically radical resection of both the primary colorectal carcinoma and the liver metastases was performed. | 30 days postoperatively |
| Intraoperative blood loss | Intraoperative blood loss in milliliters | During the surgical procedure |
| Operative time | Operative time in minutes | During the surgical procedure |
| Conversion to open surgery | Intra-operative conversion to an open or hand-assisted procedure in the minimally invasive group | During the surgical procedure |
| Mortality | Postoperative mortality | 90 days postoperatively |
| Red blood cell transfusion | Intraoperative red blood cell transfusion | During the surgical procedure |
| Intraoperative incidents | Intraoperative unfavourable incidents | During the surgical procedure |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |