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| ID | Type | Description | Link |
|---|---|---|---|
| 00012098 | Other Identifier | IRB | |
| 00018699 | Other Identifier | FWA |
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studying how the cortical auditory evoked potentials differ in children who stutter from who do not stutter and how these potentials change with therapy
Measuring amplitude and latency of P1, N1, P2 N2 between a group with developmental stuttering and a control group with no stuttering at baseline. Recording the potentials through passive listening to a 60dB stimulus and active speaking, describing pictures and rapid naming.
Assigning the group with stuttering to remediation exercises using fluency shaping program for 2 to 4 months then remeasuring amplitude and latency of the previously mentioned potentials.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Children who stutter | Experimental | Measuring stuttering severity and cortical auditory evoked potentials in a group of children who stutter then they will receive fluency shaping exercises for a period range from 2-4 months. Reassessment of cortical auditory evoked potentials and stuttering severity after the specified period |
|
| children who do not stutter | No Intervention | Measuring cortical auditory evoked potentials as a comparison group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fluency shaping exercises | Behavioral | Training for prolonged speech, easy onset, light contact and abdominal breathing moving from the level of single words till using short sentences describing pictures |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in latency of cortical auditory evoked potentials in children with stuttering compared to children who do do not stutter | Measuring latency in millisecond of P1, N1 using the commercial system (Interacoustic Eclipse TM) device during passive listening to a 60dB auditory stimulus and active speaking conditions | baseline: before intervention |
| Change in latency of cortical auditory evoked potentials in children with stuttering due to stuttering intervention program | Measuring latency in millisecond of P1, N1 in the group who stutter after intervention using the commercial system (Interacoustic Eclipse TM) device during passive listening to a 60dB auditory stimulus and active speaking conditions | immediately after intervention |
| Difference in amplitude of cortical auditory evoked potentials in children with stuttering compared to children who do do not stutter | Measuring amplitude in microvolt of P1, N1 using the commercial system (Interacoustic Eclipse TM) | baseline: before intervention |
| Change in amplitude of cortical auditory evoked potentials in children with stuttering due to stuttering intervention program | Measuring amplitude in microvolt of P1, N1 in the group who stutter after intervention using the commercial system (Interacoustic Eclipse TM) device during passive listening to a 60dB auditory stimulus and active speaking conditions | immediately after intervention |
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Inclusion criteria:
Exclusion criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Alaa M Radwan, MS | Contact | 0201159333807 | A_abdelhamed14@alexmed.edu.com | |
| Engy S Elhakeem, PhD | Contact | 201010566670 | engy.elhakeem@alex.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Rania M Abdou Mustafa, PhD | Otorhinolaryngology department,Faculty of Medicine, Alexandria University | Study Chair |
| Mohamed A Talaat, PhD | Otorhinolaryngology department,Faculty of Medicine, Alexandria University |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine, Alexandria universtiy | Recruiting | Alexandria | 21500 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28483259 | Background | Ismail N, Sallam Y, Behery R, Al Boghdady A. Cortical auditory evoked potentials in children who stutter. Int J Pediatr Otorhinolaryngol. 2017 Jun;97:93-101. doi: 10.1016/j.ijporl.2017.03.030. Epub 2017 Apr 3. | |
| Background | Abdou R. Assessment of Egyptian children who stutter using the standardized Arabic form of the Test of Childhood Stuttering. The Egyptian Journal of Otolaryngology. 2015;31(3):180-7. | ||
| 19796989 |
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It is not yet known if there would be a plane to make IPD available
anticipated 4 to 6 months for the data to be available
Through the Email Address A_abdelhamed14@alexmed.edu.eg
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| ID | Term |
|---|---|
| D013342 | Stuttering |
| ID | Term |
|---|---|
| D013064 | Speech Disorders |
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
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two groups group of children who stutter group of children who do not stutter
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| Engy S Elhakeem, PhD | Otorhinolaryngology department,Faculty of Medicine, Alexandria University | Study Director |
| Alaa M Radwan, MS | Otorhinolaryngology department, Faculty of Medicine, Alexandria University | Principal Investigator |
| Background |
| Duncan CC, Barry RJ, Connolly JF, Fischer C, Michie PT, Naatanen R, Polich J, Reinvang I, Van Petten C. Event-related potentials in clinical research: guidelines for eliciting, recording, and quantifying mismatch negativity, P300, and N400. Clin Neurophysiol. 2009 Nov;120(11):1883-1908. doi: 10.1016/j.clinph.2009.07.045. Epub 2009 Sep 30. |
| Result | Packman A, Attanasio J, editors. A model of the mechanisms underpinning early interventions for stuttering. Seminar presentation at the annual convention of the American Speech-Language and Hearing Association Philadelphia, USA; 2010. |
| 14502069 | Result | Cone-Wesson B, Wunderlich J. Auditory evoked potentials from the cortex: audiology applications. Curr Opin Otolaryngol Head Neck Surg. 2003 Oct;11(5):372-7. doi: 10.1097/00020840-200310000-00011. |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |