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Gastric intestinal metaplasia(GIM) is an important stage in the gastric cancer(GC). With technical advance of image-enhanced endoscopy (IEE), studies have demonstrated IEE has high accuracy for diagnosis of GIM. The endoscopic grading system (EGGIM), a new endoscopic risk scoring system for GC, have been shown to accurately identify a wide range of patients with GIM. However, the high diagnostic accuracy of GIM using IEE and EGGIM assessments performed all require much experience, which limits the application of EGGIM. The investigators aim to design a computer-aided diagnosis program using deep neural network to automatically evaluate the extent of IM and calculate the EGGIM scores.
Globally, gastric cancer is the fifth most prevalent malignancy and the third leading cause of cancer mortality. Gastric intestinal metaplasia (GIM) is an intermediate precancerous gastric lesion in the gastric cancer cascade. Studies have shown that the 5-year cumulative incidence of gastric cancer in IM patients ranges from 5.3% to 9.8% . With technical advance of image-enhanced endoscopy (IEE), studies have demonstrated IEE has high accuracy for diagnosis of GIM. The endoscopic grading system (EGGIM), a new endoscopic risk scoring system for GC, have been shown to accurately identify a wide range of patients with GIM. However, The high diagnostic accuracy of GIM using IEE and EGGIM assessments performed all require much experience, which limits the application of EGGIM. The investigators aim to design a computer-aided diagnosis program using deep neural network to automatically evaluate the extent of IM and calculate the EGGIM scores.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group for training the algorithm | This group of images is used for training the algorithm of the artificial intelligence | ||
| group for testing the algorithm | This group of images is used for testing the algorithm of the artificial intelligence |
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| Measure | Description | Time Frame |
|---|---|---|
| The specificity of AI model to assess the degree of intestinal metaplasia in an endoscopic picture | The specificity of AI model to assess the degree of intestinal metaplasia in an endoscopic picture | 2 years |
| The accuracy of AI model to assess the degree of intestinal metaplasia in an endoscopic picture | The accuracy of AI model to assess the degree of intestinal metaplasia in an endoscopic picture | 2 years |
| The sensitivity of AI model to assess the degree of intestinal metaplasia in an endoscopic picture | The sensitivity of AI model to assess the degree of intestinal metaplasia in an | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy of the experienced endoscopists to assess the degree of intestinal metaplasia | Accuracy of the experienced endoscopists to assess the degree of intestinal metaplasia in an endoscopic picture | 2 years |
| Accuracy of the inexperienced endoscopists to assess the degree of intestinal metaplasia |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutive patients who receive the IEE examination and screened that fulfill the eligibility criteria at Qilu Hospital, Shandong University will be enrolled into the study
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| yanqing Li, MD, PHD | Contact | 0531182169385 | liyanqing@sdu.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| yanqing Li, MD, PHD | Qilu Hospital of Shandong University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Gastrology, QiLu Hospital, Shandong University | Recruiting | Jinan | Shandong | 250012 | China |
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Accuracy of the inexperienced endoscopists to assess the degree of intestinal metaplasia in an endoscopic picture |
| 2 years |
| Inter-observer agreement among experienced endoscopists in identifying the degree of intestinal metaplasia | Inter-observer agreement among experienced endoscopists in identifying the degree of intestinal metaplasia in an endoscopic picture | 2 years |
| Inter-observer agreement among inexperienced endoscopists in identifying degree of intestinal metaplasia | Inter-observer agreement among inexperienced endoscopists in identifying degree of intestinal metaplasia in an endoscopic picture | 2 years |