Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery

Effect of the Deep Neuromuscular Block on Postoperative Delirium in Elderly Patients Undergoing Lumbar Surgery

The effect of deep neuromuscular blockade (NMB) during spine surgery reduced postoperative pain and bleeding in recent studies. Therefore by reducing these two factors, which were the contributing factors for postoperative delirium, deep NMB is expected to reduce the postoperative delirium. This study was designed to determine whether the deep NMB lowered the incidence of delirium after lumbar surgery.

Inclusion Criteria:

• Aged 70 and more;
• Scheduled for an elective lumbar spine surgery;
• ASA physical status 1-3

Exclusion Criteria:

• Diagnosed neuromuscular disorder;
• Contraindications to the study drug, e. g. known allergy or hypersensitivity, hypotension, bradycardia, higher grade atrioventricular block;
• Patient with pre-existing cognitive impairment or dementia