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Effects of left atrial pressure-guided ventricular rate changes on cardiac function after atrioventricular node ablation combined with left bundle branch pacing
Effects of left atrial pressure-guided ventricular rate changes on cardiac function after atrioventricular node ablation combined with left bundle branch pacing. For patients with non-valvular atrial fibrillation who received atrioventricular node ablation combined with left bundle branch pacing in our hospital, a left atrial pressure catheter was used to monitor atrial pressure during the operation, and a lower average atrial pressure was obtained by adjusting the pacing frequency of the pacemaker. In a randomized controlled manner, the postoperative echocardiography, cardiothoracic ratio, cardiac function, etc. were compared between patients without atrial pressure monitoring and those who received atrial pressure adjustment, in order to clarify the effect of left atrial pressure-guided ventricular rate adjustment on atrioventricular node ablation combined with left bundle Benefit of pacing patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LAP Group | Experimental | Control of left atrial pressure changes by adjusting pacemaker frequency |
|
| Control Group | No Intervention | General pacemaker rate setting |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| left atrial pressure regulation | Procedure | For patients after atrioventricular node ablation combined with left atrial appendage closure, the regulation of left atrial pressure can be controlled by adjusting the frequency of pacemaker. |
| Measure | Description | Time Frame |
|---|---|---|
| EF% | aortic vestibular ejection fraction | 1-year |
| Measure | Description | Time Frame |
|---|---|---|
| cardiovascular all-cause mortality | Proportion of patients dying from cardiovascular causes | 1week |
| Hospitalizations for heart failure | Hospitalizations for heart failure |
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Inclusion Criteria:
18-85 years old atrial fibrillation patients
Exclusion Criteria:
There is a history of pacemaker implantation; patients after coronary artery bypass grafting; severe coronary stenosis or occlusion cannot be treated with reperfusion;
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| Name | Affiliation | Role |
|---|---|---|
| Yawei Xu, Ph.D | Shanghai 10th People's Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jun Zhang | Shanghai | Shanghai Municipality | 200072 | China |
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After the research results are published;2 years;
open
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| 1 years |
| D013568 |
| Pathological Conditions, Signs and Symptoms |