Comparison of Remimazolam and Dexmedetomidine for Intraoperative Sedation

Comparison of Remimazolam and Dexmedetomidine for Intraoperative Sedation During Regional Block

The purpose of this study is to compare the sedation efficacy of dexmedetomidine and remimazolam for intraoperative sedation during regional block.

Inclusion Criteria:

• Patient scheduled for lower extremity surgery under regional anesthesia, aged 19-70, of ASA class I or II.

Exclusion Criteria:

• Patient refusal
• Contraindications to regional or neuraxial anesthesia (patient refusal, increased intracranial pressure, infection at puncture site, underlying neurologic disease, severe hypovolemia, aortic or mitral stenosis, thrombocytopenia or coagulopathy)
• Contraindications to dexmedetomidine or remimazolam administration
• Allergy to dexmedetomidine or remimazolam
• Baseline MOAA/S score of 4 or less
• Pregnancy
• Other conditions considered unsuitable by the investigators