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The purpose of the study is to understand the effect of dietary fiber on patients with polycystic ovary syndrome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| dietary fiber intervention | Experimental | Participants take a certain amount of dietary fiber per day. |
|
| Placebo | Placebo Comparator | Participants take a certain amount of placebo (Maltodextrin) per day. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dietary intervention | Dietary Supplement | dietary fiber (Inulin 4g,Resistant Starch 4g,β-glucan 2g) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in gut microbiota | Study the gut microbiota change of stool samples between placebo group and intervention group | before and after 2,4,8,12 weeks of intervention |
| Changes in metabolomics | Study the netabolomics change of stool samples between placebo group and intervention group | before and after 2,4,8,12 weeks of intervention |
| Changes in endocrine hormones | Study the hormones change of blood samples between placebo group and intervention group | before and after 12 weeks of intervention |
| Changes in ovarian volume | The size of each ovary will be determined using transvaginal ultrasonography for each participant in early follicular phase. | before and after 12 weeks of intervention |
| Changes in the number of follicles | The number of follicles of each ovary will be determined using transvaginal ultrasonography for each participant in early follicular phase. | before and after 12 weeks of intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jie Qiao, PhD | Contact | +86 010-82265080 | jie.qiao@263.net |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University Third Hospital | Recruiting | Beijing | Beijing Municipality | 100191 | China |
Patients' information is requested to be confidential.
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| ID | Term |
|---|---|
| D011085 | Polycystic Ovary Syndrome |
| ID | Term |
|---|---|
| D010048 | Ovarian Cysts |
| D003560 | Cysts |
| D009369 | Neoplasms |
| D010049 | Ovarian Diseases |
| D000291 |
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| ID | Term |
|---|---|
| D004035 | Diet Therapy |
| ID | Term |
|---|---|
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
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| Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D006058 | Gonadal Disorders |
| D004700 | Endocrine System Diseases |