Vitamin B12 and Dextrose for Median Nerve Hydrodissection

The Effects of Vitamin B12 and Dextrose on the Ultrasound-guided Median Nerve Hydrodissection

Carpal tunnel syndrome is the most common peripheral entrapment neuropathy of the upper limb. Previous experiments found that ultrasound-guided median nerve hydrodissection with 5% dextrose water could ameliorate the condition of carpal tunnel syndrome. Oral administration of vitamin B 12 had been reported to reduce the discomfort from peripheral neuropathy although the level of evidence is not strong. This prospective, double-blind randomized control trial aims to compare the effects of different kinds of the injection agents on carpal tunnel syndrome.

Inclusion Criteria:

• Age between 20-80 year-old.
• Diagnosis (carpal tunnel syndrome) was confirmed using an electrophysiological study.

Exclusion Criteria:

• Previously undergone wrist surgery or steroid injection for CTS
• Thrombocytopenia
• Coagulopathy
• Inflammation status
• Polyneuropathy
• Brachial plexopathy
• Cervical radiculopathy
• Autoimmune disease
• Malignancy
• Pregnancy

Thoracic outlet syndrome