aim of the study will be conducted to compare the effect of MTA fill apex sealer and endo sequence bioceramic sealer in obturation on the intenisty of postoperative pain and the incidence of post operative swelling in patient with necrotic teeth .

Inclusion Criteria:

• Patients requiring root canal treatment of single canal necrotic teeth.
• Patient from 18 to 60 years old
• Patients with Asymptomatic apical periodontitis.
• Teeth presenting with no clinical symptoms and with a periapical score from 2 to 4 according to Orstavik et al

Exclusion Criteria:

• Teeth with incompletely formed apex

  • Teeth requiring retreatment
  • Patients having complicating systemic disease such as diabetes, malignancy, pregnancy, central nervous system disorders, Cardiovascular system disorders, respiratory disorders, asthma patients, psychiatric disorders, immunocompromised patients
  • Patients taking anti-inflammatory or antibiotics
  • Patients giving history of analgesic or antibiotic intake 1 week before treatment
  • Patients below 18 years of age

• Patients above 65 years of age

  • Patients having history of peptic ulcer or gastrointestinal bleeding
  • Teeth affected with periodontal disease