Description of Physical Activity Effect on Neuromuscular Fatigue of Older People

Description of Physical Activity Effect on Neuromuscular Fatigue of Older People

There is a decrease in cardiovascular and neuromuscular functions, which leads to reduced performance with advancing age. Physical activity provides health benefits, prevents and treats cardiovascular and neuromuscular disease. The aim of this project is to describe cardiovascular and neuromuscular function in active and sedentary subjects of different ages.

With advancing age, there is a decrease in cardiovascular and neuromuscular functions, which leads to reduced performance and increases the likelihood that older people will lose their independence. Physical activity provides health benefits, prevents and treats cardiovascular and neuromuscular disease. Indeed, recent data support the idea that it is fitness level, not age that explains physiological responses to exercise. However, although there are data about how quickly cardiovascular and neuromuscular functions decline throughout life, less is known on the extent physical activity can help mitigate the loss of these functions. The aim of this project is therefore to describe cardiovascular and neuromuscular function in active and sedentary subjects of different ages.

Inclusion Criteria:

• Aged 18 to 35 for the young group, between 65 and 80 for the old group and over 80 for the very old group.
• Signed consent for the study obtained
• Subject affiliated or entitled to a social security scheme

Exclusion Criteria:

• Pathology or surgical intervention causing a locomotor disorder
• Neurological, cardiovascular or psychological pathology
• Participants will be excluded if resting or exercise ECG responses show any abnormality, or if resting Heart Rate (HR) > 100 bmp, resting blood pressure > 144 (systolic) / 95 (diastolic) mmHg, pulmonary and or cardiac disease that could affect the health of the participant (arrhythmias and stroke)
• Mini-Mental State Examination score < 20 (>80 years old)
• Significant change in the amount of physical practice over the last 5 years.