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Cardiac and thoracic surgery are major procedures. In order to estimate the operative risk, many scores have been developed, including the Euroscore 2 in cardiac surgery. However, the Euroscore has limitations since it does not assess all the parameters that may influence postoperative complications, such as the patient's general condition or the status of his or her functional reserves.
However, it has been shown that the preoperative functional reserves have a significant impact on the patient's risk of developing postoperative complications following major surgery. In addition, there is a strong association between cardiac failure and a well-described decrease in peripheral muscle lean mass (sarcopenia) in patients older than 65 years.
Usually, a nutritional assessment is performed during the pre-anesthesia consultation. This assessment is based on clinical and biological criteria that are not totally predictive of the patient's functional reserve status.
Lean body mass (muscle) is a well-validated marker for the assessment of patients' functional reserves. However, the techniques used to date are complex and require radiation.
This study aims to use ultrasound of muscle groups (respiratory muscles - Quadriceps muscle - Diaphragm) to study the relationship between preoperative muscle mass and postoperative complications in patients over 65 years of age undergoing cardiac or thoracic surgery.
This is a prospective observational study to be conducted at the Dijon University Hospital by the cardiovascular anesthesia-intensive care department. A total of 300 patients will participate in this study, and we have planned to complete the project over a 2-year period. The participating patients (if they do not present any exclusion criteria and are not opposed to inclusion) will be included and undergo a muscle ultrasound in the cardiovascular surgery department or the thoracic and pulmonary surgery department the day before their intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cardiology patient | Patient requiring cardiac surgery with bypass |
| |
| Pneumology patient | Patient requiring lung surgery with resection of at least one lobe |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasound of the abdominal wall muscles | Other | the measurements will be performed during inspiration and expiration to take into account variability during the respiratory cycle. The examination is performed bilaterally and comparatively and lasts between 3 and 5 minutes. |
| Measure | Description | Time Frame |
|---|---|---|
| Onset of acute renal failure | Within 30 days after surgery | |
| Occurrence of a respiratory complication | Occurrence of acute respiratory failure in cardiac surgery and occurrence of a severe extra-respiratory complication according to the european perioperative clinical outcome definition in pulmonary surgery | Within 30 days after surgery |
| Occurrence of a cardiovascular complication | Within 30 days after surgery | |
| Occurrence of an infectious complication | Within 30 days after surgery | |
| Death | Within 30 days after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Patient requiring cardiac or thoracic surgery
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chu Dijon Bourgogne | Dijon | 21000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41238178 | Result | Berthoud V, Nguyen M, Vinay J, Perrot J, Pages PB, Guinot PG, Bouhemad B. Increase in Diaphragm and Expiratory respiratory muscles thickness is not associated with postoperative pulmonary complications after thoracic surgery: A prospective ultrasound cohort study. Anaesth Crit Care Pain Med. 2026 Jul;45(4):101683. doi: 10.1016/j.accpm.2025.101683. Epub 2025 Nov 12. |
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| Ultrasound quadricipital | Other | The examination is performed bilaterally and comparatively and takes between 3 and 5 minutes. |
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| Ultrasound of the diaphragm | Other | The examination is performed bilaterally and comparatively and takes between 5 and 10 minutes. |
|
| Ultrasound of the inter-costal muscles | Other | measurements performed bilaterally on a patient in a half-sitting position at 45° and in spontaneous ventilation |
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| Ultrasound of the inter-costal muscles | Other | In spontaneous ventilation, lying down, arms by the side of the body, palms up, head down |
|