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Critical illness is associated with ICU acquired weakness and diaphragmatic dysfunction.
Ultrasound can evaluate the muscle mass non invasively and provides the ability for a muscle follow up during and after the ICU stay. Magnetic stimulation of the phrenic nerves and the measure of the end expiratory tracheal pressure with an occlusion valve allows to evaluate the diaphragm force production in mechanically ventilated patients.
The aim of the present study is to constitute an image bank and to describe the muscle mass and function recovery in critically ill patients.
Critical illness is associated with ICU acquired weakness and diaphragmatic dysfunction.
Ultrasound can evaluate the muscle mass non invasively and provides the ability for a muscle follow up during and after the ICU stay. Magnetic stimulation of the phrenic nerves and the measure of the end expiratory tracheal pressure with an occlusion valve allows to evaluate the diaphragm force production in mechanically ventilated patients.
The aim of the present study is to constitute an image bank and to describe the mass and function recovery in critically ill patients.
Ultrasound and clinical data will be collected and analysed during the ICU stay.
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| Measure | Description | Time Frame |
|---|---|---|
| Ultrasound characteristics of the quadriceps | Changes in ultrasound characteristics of the quadriceps : cross sectional area of quadriceps (cm2) | Since admission at day 0 and measured repetitively by 48 hours untildischarge from ICU or date of death from any cause, whichever came first, assessed up to day 28 |
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| Measure | Description | Time Frame |
|---|---|---|
| Ultrasound characteristics of the biceps | Changes in ultrasound characteristics of the biceps : thickness of the biceps (mm) | Since admission at day 0 and measured repetitively by 48 hours untildischarge from ICU or date of death from any cause, whichever came first, assessed up to day 28 |
| Ultrasound characteristics of the diaphragm |
Inclusion Criteria:
Exclusion criteria:
- Pregnancy, age below 18, absence of consent
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Critically ill patients with at least one organ failure and an estimated duration of ICU stay of 3 days or more
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| Name | Affiliation | Role |
|---|---|---|
| BORIS JUNG, MD, PhD | University Hospital, Montpellier | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Uhmontpellier | Montpellier | 34295 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34255974 | Derived | Aarab Y, Flatres A, Garnier F, Capdevila M, Raynaud F, Lacampagne A, Chapeau D, Klouche K, Etienne P, Jaber S, Molinari N, Gamon L, Matecki S, Jung B. Shear Wave Elastography, a New Tool for Diaphragmatic Qualitative Assessment: A Translational Study. Am J Respir Crit Care Med. 2021 Oct 1;204(7):797-806. doi: 10.1164/rccm.202011-4086OC. | |
| 32014005 |
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NC
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| ID | Term |
|---|---|
| D016638 | Critical Illness |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Ultrasound characteristics of the diaphragm : thickness (mm) |
| Since admission at day 0 and measured repetitively by 48 hours untildischarge from ICU or date of death from any cause, whichever came first, assessed up to day 28 |
| Flatres A, Aarab Y, Nougaret S, Garnier F, Larcher R, Amalric M, Klouche K, Etienne P, Subra G, Jaber S, Molinari N, Matecki S, Jung B. Real-time shear wave ultrasound elastography: a new tool for the evaluation of diaphragm and limb muscle stiffness in critically ill patients. Crit Care. 2020 Feb 3;24(1):34. doi: 10.1186/s13054-020-2745-6. |