Efficacy and Safety of Etomidate Sedation in Gastric Endoscopic Submucosal Dissection

A Comparative Study of the Efficacy and Safety of Etomidate Compared to Propofol in Gastric Endoscopic Submucosal Dissection: a Prospective, Single-center, Randomized, Double-blind, Non-inferiority Study

During endoscopy, the patient is sedated to relieve pain and improve the ease of the procedure. Sedation endoscopy using propofol is effective, but has the disadvantage that cardiopulmonary side effects are frequently observed. However, etomidate is known to have hemodynamic and respiratory stability.The purpose of this study was to compare the efficacy and safety of etomidate and propofol in sedated gastric endoscopic submucosal dissection.

Inclusion Criteria:

• Age 19-80
• American Society of Anesthesiologists Physical Status Classification System (ASA) score of I, II, III
• Scheduled endoscopy

Exclusion Criteria:

• Pregnancy
• Previous study History of hypersensitivity to drugs or substances containing soy or egg ingredients
• Those who think that tracheal intubation will be difficult
• Obstructive sleep apnea
• History of side effects from previous sedatives
• People with severe liver disease, kidney disease, or heart disease
• Those who want a non-sleeping endoscope
• A person who refuses to provide consent
• SBP < 80mmHg or SpO2 < 90%
• Patients with adrenocortical dysfunction, chronic steroid users