Neurofeedback for Borderline Personality Disorder | NCT05398627 | Trialant

Neurofeedback for Borderline Personality Disorder | NCT05398627 | Trialant

Sponsor/Collaborators Module

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Amygdala Neurofeedback	Experimental	Participants will undergo real-time fMRI neurofeedback training to increase their amygdala response while recalling positive autobiographical memories. 2 sessions will occur within a one week period.	Device: Amygdala Neurofeedback

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Amygdala Neurofeedback	Device	real-time feedback on the hemodynamic response of the amygdala during positive autobiographical memory recall	Amygdala Neurofeedback

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Change from Baseline in Borderline Scale from the Personality Assessment Inventory at 12 weeks	Assessment of severity of borderline symptoms. This scale contains 24 items rated on a four-point scale (0=false to 3=very true). Scores range from 0-72, and are converted to T scores, with higher scores indicating more borderline symptoms. Scores below 59 indicate healthy, scores at or above 70T indicate the respondent is likely to have borderline personality disorder.	Baseline vs 12 weeks

Secondary Outcomes

Measure	Description	Time Frame
Change from Baseline in Beck Depression Inventory at 12 weeks	Assessment of severity of depressive symptoms. This is a 21 item self-report scale with items rated from 0-3 and scores ranging from 0 to 63 with higher scores indicating worse depression. A score less than 13 is considered to be in the healthy range, scores 14-19 indicate mild depression, scores 20-28 indicate moderate depression, scores 29-63 indicate severe depression.

Contacts/Locations Module

Condition Browse Module