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Type 1 diabetes is an autoimmune disease with absence of insulin secretion. Blood sugar is a physiological variable that reflets for blood glucose concentration. Blood sugar level fluctuates, especially during physical activity.
Sports activity would increase insulin sensitivity, improve lifestyle and, by extension, promote glycemic balance. However, glycemic balance will be disturbed by physical activity with higher risk of hypoglycemia and hyperglycemia.
Moreover, hypoglycemia and hyperglycemia will impact body functions. Perceptions of blood sugar variations during physical exercise and their influences on sports performance have not been studied, whether in type 1 diabetes patients or healthy subjects.
The aim of the study is to evaluate the perception of blood sugar variations in healthy subjects and type 1 diabetes patients during physical activity
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| "Type 1 diabetes" group | Experimental | "type 1 diabetes" group: patients with type 1 diabetes |
|
| "healthy" group | Active Comparator | "healthy" group : subjects without type 1 diabetes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physical activity | Other | Physical activity: 10 km run on a treadmill |
|
| Measure | Description | Time Frame |
|---|---|---|
| blood sugar | Blood sugar evaluated in g/L via continuous blood glucose measurement | Day 0 |
| Feeling lucidity | Lucidity, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "not at all lucid" to "completely lucid" | Day 0 |
| Feeling fatigue | hydratation, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "no feeling of dehydration" to "dehydrated" | Day 0 |
| feeling hungry | hungry, which is a symptom of hyperglycaemia and hypoglycaemia, assessed by visual analog scale (between "no feeling of hunger" to "hungry" | Day 0 |
| average speed per kilometer Sports performance | Sports performance evaluated by average speed per kilometer of the 10 km run on a treadmill | Day 0 |
| total running time | Sports performance evaluated by total running time of the 10 km run on a treadmill | Day 0 |
| average running speed | Sports performance evaluated by average running speed of the 10 km run on a treadmill | Day 0 |
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Inclusion Criteria:
Exclusion Criteria:
Male
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Philippe JOLY, MCU-HDR | Contact | 0326918822 | +33 | philippe.joly@univ-reims.fr |
| Coralie BARBE, MD | Contact | 0326918822 | +33 | currs@univ-reims.fr |
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| ID | Term |
|---|---|
| D003922 | Diabetes Mellitus, Type 1 |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| D004700 | Endocrine System Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D001519 | Behavior |