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| ID | Type | Description | Link |
|---|---|---|---|
| 2016-A01837-44 | Other Identifier | 2016-A01837-44 |
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The type 1 diabetes is a common chronic disease characterised by the stop of production of insulin by the pancreas. A lot of factors modify blood glucose. The objective is to study the effect of type 1 diabetes on the use of energy substrates (fats and carbohydrates) during exercise of increasing intensity by a comparison with non-diabetic controls children.
The type 1 diabetes is a common chronic disease characterised by the stop of production of insulin by the pancreas. A lot of factors modify blood glucose. The objective is to study the effect of type 1 diabetes on the use of energy substrates (fats and carbohydrates) during exercise of increasing intensity by a comparison with non-diabetic controls children.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| type 1 diabetes | Experimental | Comparison between infants with type 1 diabetes and infants without type 1 diabetes during exercise : |
|
| without type 1 diabetes | Active Comparator | Comparison between infants with type 1 diabetes and infants without type 1 diabetes during exercise : |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| controlled physical activity | Procedure | Comparison between infants with type 1 diabetes and infants without type 1 diabetes during exercise : |
|
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of substrate utilization between infants with type 1 diabetes and infants without type 1 diabetes during exercise | Measurements will be carried out by indirect calorimetry and the relationship between CO2 et O2 (Metamax) | at day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| hormonal regulation of blood glucose | insulin, glucagon, adrenaline, cortisol and growth hormone will be metered according to their half life until 2 hours after physical activity (T12, T20, T40, T60, T120) | at day 1 |
| lipoxmax : the intensity for wich lipid oxydation is maximum will be carried out by indirect calorimetry |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Patrick LACARIN | Contact | 04 73 75 11 95 | placarin@chu-clermontferrand.fr |
| Name | Affiliation | Role |
|---|---|---|
| Daniel TERRAL | University Hospital, Clermont-Ferrand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Clermont-Ferrand | Recruiting | Clermont-Ferrand | 63003 | France |
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no masking is used. All involved know the identity of the intervention assignment
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during exercise |
| at day 1 |
| Comparison between infants during 10 days before and 4 days after exercise of blood glucose modification | Comparison of curves of interstitial blood glucose measured with Freestyle® | 10 days before and 4 days after exercise of blood glucose modification |
| ID | Term |
|---|---|
| D003922 | Diabetes Mellitus, Type 1 |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D001519 | Behavior |
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