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This study will primarily test various phytonutrient-based supplements to see which gets absorbed into the body the best. The study will secondarily look at inflammatory markers in the urine to determine any change.
This study will primarily test various phytonutrient-based supplements to see which gets absorbed into the body the best. 120 mg of curcumin from brands Meriva, CurcElite, Lonvida, UltraCur, NovaSol. The study will secondarily look at inflammatory markers in the urine to determine any change.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Meriva | Other | 120 mg of curcumin in Meriva. |
|
| Longvida | Other | 120 mg of curcumin Longvida. |
|
| NovaSol | Other | 120 mg of curcumin NovaSol |
|
| CurcElite | Other | 120 mg of curcumin CurcElite |
|
| UltaCur | Other | 120 mg of curcumin Ultracur |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Curcumin | Dietary Supplement | Oral supplement |
|
| Measure | Description | Time Frame |
|---|---|---|
| Bioavailability | Blood Plasma | 0, 1, 2, 4, and 12 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| David Roberts, MPH | Contact | 810777687 | research@epiceuticallabs.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| David Roberts | Recruiting | Charlottesville | Virginia | 22902 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30006023 | Result | Jamwal R. Bioavailable curcumin formulations: A review of pharmacokinetic studies in healthy volunteers. J Integr Med. 2018 Nov;16(6):367-374. doi: 10.1016/j.joim.2018.07.001. Epub 2018 Jul 4. |
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Blood plasma and urine samples will be collected for five different times over five different supplements.
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| ID | Term |
|---|---|
| D007249 | Inflammation |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D003474 | Curcumin |
| ID | Term |
|---|---|
| D036381 | Diarylheptanoids |
| D006536 | Heptanes |
| D000473 | Alkanes |
| D006839 | Hydrocarbons, Acyclic |
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| D006838 |
| Hydrocarbons |
| D009930 | Organic Chemicals |
| D002396 | Catechols |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |